Endocrine Abstracts

It is well established that the majority of the immunohistochemically confirmed gonadotroph adenomas are hormonally silent, accounting almost 64% of all clinically nonfunctioning pituitary adenomas. Whereas clinically functioning gonadotroph adenomas (FGA) are very rare and the exact prevalence is not known. We present the case of a FGA in a premenopausal. A 31-year-old female presented in the ED with oligomenorrhea for 11 months, abdominal pain and distention over the precedi...

A proportion of prolactinomas exhibit aggressive features (including invasiveness, relevant growth despite adequate dopamine agonist treatment, and recurrence potential) and few may exhibit metastasizing potential (carcinomas). We present an uncommon case of intra-orbital spread from a large infiltrative prolactinoma, with excellent response to temozolomide and a systematic review of the literature. A 55y.o male patient presented with generalized weakness and hyponatraemia. Fu...